Prevention of Renal Scarring from Pyelonephritis in Nonhuman Primates by Vaccination
نویسندگان
چکیده
JAMES A. ROBERTS,l.2* M. BERNICE KAACK,1'2 GARY BASKIN,2 AND STEFAN B. SVENSON3 Department of Urology, Tulane University School ofMedicine, New Orleans, Louisiana 701121 Departments of Urology and Pathology, Tulane Regional Primate Research Center, 18703 Three Rivers Road, Covington, Louisiana 70433,2* and Department of Vaccine Research, National Bacteriological Laboratory, and Karolinska Institute, Stockholm S-10521, Sweden3
منابع مشابه
Prevention of renal scarring from pyelonephritis in nonhuman primates by vaccination with a synthetic Escherichia coli serotype O8 oligosaccharide-protein conjugate.
Rhesus monkeys were vaccinated with a synthetic Escherichia coli serotype O8 oligosaccharide-protein conjugate. Using our experimental pyelonephritis monkey model, we tested whether such immunization was protective against the renal damage from inflammation following experimental infection with a P-fimbriated O-antigenically homologous E. coli strain. The vaccination did not significantly alter...
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